| 6/2/2025 | Mayhem | Waive | RB Patrick Taylor (SF), DB Ar'Darius Washington (BAL) |
| Bruins | Waive | DB Josh Metellus (MIN) |
| Dawgs | Waive | RB Jerome Ford (CLE) |
| 3/12/2025 | Avengers | Move | DL Christian Wilkins (LV), LB Jeremiah Owusu-Koramoah (CLE), DB Jaquan Brisker (CHI) [To IR], WR Chris Olave (NO) |
| Roughness | Move | LB Jermaine Johnson (JET) [To IR] |
| Move | WR Chris Godwin (TB), LB Jermaine Johnson (JET) |
| Deplorables | Move | WR Allen Lazard (JET), WR Brandon Aiyuk (SF), DL Jonathan Allen (WAS) |
| BillsMafia | Move | LB Matt Milano (BUF) |
| EvilEmpire | Move | QB Dak Prescott (DAL) |
| Minutemen | Move | LB Christian Harris (HOU), RB Austin Ekeler (WAS), LB Logan Wilson (CIN) |
| Move | LB De'Vondre Campbell (SF) |
| Players | Move | RB Jordan Mason (SF), LB Troy Reeder (LAR) |
| Mayhem | Move | LB Junior Colson (LAC), DB Jalen Pitre (HOU), RB Nick Chubb (CLE), DL Aidan Hutchinson (DET) |
| Bruins | Move | RB J.K. Dobbins (LAC), WR Christian Kirk (JAX), LB Dre Greenlaw (SF), LB Azeez Al-Shaair (HOU) |
| Dragons | Move | LB Bradley Chubb (MIA), LB Alex Singleton (DEN), LB Shaq Thompson (CAR) |
| Dawgs | Move | RB Christian McCaffery (SF), WR Rashid Shaheed (NO), LB Ja'Whaun Bentley (NE) |
| NittanyLions | Move | DL Demarcus Lawrence (DAL) |